| WIAC Football |
| September |
| Week 1 |
| 09/02/21 |
East Texas Baptist at UW-Platteville |
Box Score |
| 09/04/21 |
Luther College, IA at UW-Eau Claire |
Box Score |
| 09/04/21 |
UW-La Crosse at Dakota State, SD |
Box Score |
| 09/04/21 |
UW-Oshkosh at Huntingdon College, AL |
Box Score |
| 09/04/21 |
Elmhurst University, IL at UW-River Falls |
Box Score |
| 09/04/21 |
UW-Stevens Point at Mayville State, ND |
Box Score |
| 09/04/21 |
UW-Stout at Presentation College, SD |
Box Score |
| 09/04/21 |
Carthage College, WI at UW-Whitewater |
Box Score |
| Week 2 |
| 09/11/21 |
UW-Eau Claire at Loras College, IA |
Box Score |
| 09/11/21 |
University of Dubuque, IA at UW-La Crosse |
Box Score |
| 09/11/21 |
UW-Oshkosh at Northern Michigan |
Box Score |
| 09/11/21 |
UW-Platteville at Bethel University, MN |
Box Score |
| 09/11/21 |
UW-River Falls at Hendrix College, AR |
Box Score |
| 09/11/21 |
UW-Stevens Point at Simpson College, IA |
Box Score |
| 09/11/21 |
St. Norbert College at UW-Stout |
Box Score |
| 09/11/21 |
UW-Whitewater at Salisbury University, MD |
Box Score |
| Week 3 |
| 09/18/21 |
UW-La Crosse at Grand Valley State, MI |
Box Score |
| 09/18/21 |
UW-Platteville at Franklin College, IN |
Box Score |
| 09/18/21 |
UW-River Falls at Northwestern, MN |
Box Score |
| 09/18/21 |
UW-Stout at UW-Stevens Point |
Box Score |
| 09/18/21 |
Berry College, GA at UW-Whitewater |
Box Score |
| Week 4 |
| 09/25/21 |
UW-Eau Claire at Albion College, MI |
Box Score |
| October |
| Week 5 |
| 10/02/21 |
UW-Eau Claire at UW-Stevens Point |
Box Score |
| 10/02/21 |
UW-La Crosse at UW-River Falls |
Box Score |
| 10/02/21 |
UW-Oshkosh at UW-Platteville |
Box Score |
| 10/02/21 |
UW-Stout at UW-Whitewater |
Box Score |
| Week 6 |
| 10/09/21 |
UW-Stout at UW-Eau Claire |
Box Score |
| 10/09/21 |
UW-Oshkosh at UW-La Crosse |
Box Score |
| 10/09/21 |
UW-Platteville at UW-Whitewater |
Box Score |
| 10/09/21 |
UW-River Falls at UW-Stevens Point |
Box Score |
| Week 7 |
| 10/16/21 |
UW-River Falls at UW-Eau Claire |
Box Score |
| 10/16/21 |
UW-La Crosse at UW-Platteville |
Box Score |
| 10/16/21 |
UW-Whitewater at UW-Oshkosh |
Box Score |
| 10/16/21 |
UW-Stevens Point at UW-Stout |
Box Score |
| Week 8 |
| 10/23/21 |
UW-Eau Claire at UW-Oshkosh |
Box Score |
| 10/23/21 |
UW-Stout at UW-La Crosse |
Box Score |
| 10/23/21 |
UW-Stevens Point at UW-Platteville |
Box Score |
| 10/23/21 |
UW-Whitewater at UW-River Falls |
Box Score |
| Week 9 |
| 10/30/21 |
UW-Eau Claire at UW-Whitewater |
Box Score |
| 10/30/21 |
UW-La Crosse at UW-Stevens Point |
Box Score |
| 10/30/21 |
UW-Oshkosh at UW-Stout |
Box Score |
| 10/30/21 |
UW-Platteville at UW-River Falls |
Box Score |
| November |
| Week 10 |
| 11/06/21 |
UW-Platteville at UW-Eau Claire |
Box Score |
| 11/06/21 |
UW-La Crosse at UW-Whitewater |
Box Score |
| 11/06/21 |
UW-Stevens Point at UW-Oshkosh |
Box Score |
| 11/06/21 |
UW-River Falls at UW-Stout |
Box Score |
| Week 11 |
| 11/13/21 |
UW-Eau Claire at UW-La Crosse |
Box Score |
| 11/13/21 |
UW-River Falls at UW-Oshkosh |
Box Score |
| 11/13/21 |
UW-Stout at UW-Platteville |
Box Score |
| 11/13/21 |
UW-Whitewater at UW-Stevens Point |
Box Score |
| Round 1
:: Playoffs |
| 11/20/21 |
UW-La Crosse at Albion College, MI |
Box Score |
| 11/20/21 |
Greenville College, IL at UW-Whitewater |
Box Score |
|
Isthmus Bowl |
| 11/20/21 |
UW-River Falls vs. Washington University, MO |
Box Score |
| Round 2 :: Playoffs |
| 11/27/21 |
UW-La Crosse at North Central College, IL |
Box Score |
| 11/27/21 |
DePauw University, IN at UW-Whitewater |
Box Score |
| December |
|
Quarterfinals :: Playoffs |
| 12/04/21 |
Central College, IA at UW-Whitewater |
Box Score |
|
Semifinals :: Playoffs |
| 12/11/21 |
Mary Hardin-Baylor, TX at UW-Whitewater |
- |
|
Championship :: Playoffs |
| 12/17/21 |
- vs. - |
- |
| |
